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Pyridin-2(1H)-ones: A Promising Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

✍ Scribed by José Luis Medina-Franco; Karina Martínez-Mayorga; Cecilia Juárez-Gordiano; Rafael Castillo


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
298 KB
Volume
2
Category
Article
ISSN
1860-7179

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## Abstract An extended spectrum of HIV‐1 reverse‐transcriptase (RT) mutations in HAART‐treated patients has been recently described. To verify the possible association of previously unreported RT mutations with a decrease of phenotypic susceptibility to nucleoside (NRTIs) and non‐nucleoside (NNRTI