Pyrazolo[4,3-d]pyrimidine nucleosides. Synthesis and antiviral activity of 1-.beta.-D-ribofuranosyl-3-methyl-6-substituted-7H-pyrazolo[4,3-d]pyrimidin-7-ones
✍ Scribed by Baraldi, Pier Giovanni; Simoni, Daniele; Periotto, Vittorio; Manfredini, Stefano; Guarneri, Mario; Manservigi, Roberto; Cassai, Enzo
- Book ID
- 126973754
- Publisher
- American Chemical Society
- Year
- 1984
- Tongue
- English
- Weight
- 663 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2623
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## Abstract Pyrazolo‐[3,4‐__d__]pyrimidine‐4,6‐diones **5** and pyrazolo[4,3‐__d__]pyrimidine‐5,7‐diones **7** were synthesized by Curtius rearrangement of pyrazolic mono‐esters **2** and **3** followed by hetero‐cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.
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