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Pycnogenol attenuates cyclooxygenase 2 and matrix metalloproteinase 9 in articular chondrocytes induced by interleukin-1beta

✍ Scribed by H.-S. Lee⁎; Y.-J. Peng


Book ID
116325705
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
71 KB
Volume
50
Category
Article
ISSN
8756-3282

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## Abstract ## Objective To investigate the effects of prostaglandin D~2~ (PGD~2~) on interleukin‐1β (IL‐1β)–induced matrix metalloproteinase 1 (MMP‐1) and MMP‐13 expression in human chondrocytes and the signaling pathways involved in these effects. ## Methods Chondrocytes were stimulated with I