Induction of vascular endothelial growth factor and matrix metalloproteinase-3 (stromelysin) by interleukin-1 in human articular chondrocytes and synoviocytes
✍ Scribed by Kenji Inoue; Kayo Masuko-Hongo; Masahiro Okamoto; Kusuki Nishioka
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 251 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0172-8172
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## Abstract Basic fibroblast growth factor (FGF‐2) and matrix metalloproteinases (MMPs) play key roles in vascular remodeling. Because FGF‐2 controls a number of proteolytic activities in various cell types, we tested its effect on vascular endothelial cell expression of MMP‐3 (stromelysin‐1), a br