## Abstract The total number of cell surface glycoprotein molecules at the plasma membrane results from a balance between their constitutive internalization and their egress to the cell surface from intracellular pools and/or biosynthetic pathway. Constitutive internalization is net result of const
Putting together an MHC class I molecule
β Scribed by Marie-Jose Bijlmakers; Hidde L. Ploegh
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 855 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
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## Abstract Apart from their wellβknown function of antigen presentation in the form of peptides, major histocompatibility antigens (MHC) have been found to be unique markers of individual body odors in murine experimental models. In the current study we examined the nature and expression of solubl
The association of peptide fragments with MHC class I molecules is believed to be a requirement for the assembly of the MHC class I molecules in the endoplasmic reticulum, and transportation of the MHC molecules from the endoplasmic reticulum to the cell surface. Recently, investigators have begun t