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Purine monoribonucleotides may preferentially catalyze the synthesis of L-amino acid peptides

✍ Scribed by James C. Lacey; Ralph D. Thomas; Mark P. Staves; Vladimir Minic; Charles L. Watkins


Book ID
105557430
Publisher
Springer Netherlands
Year
1989
Tongue
English
Weight
135 KB
Volume
19
Category
Article
ISSN
1573-0875

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Papain catalyzed synthesis of glyceryl esters of BOC(Z)-protected amino acids and peptides was performed at 40-50Β°C in a 50 molar excess of glycerol. Equilibrium was achieved in 6-7 h. The maximal yield of esters (50-70%) was obtained at 10% of water and pH 3.2-3.4. A lower water concentration resul