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The application of Nα-formyl amino acid esters in the enzyme-catalyzed peptide synthesis

✍ Scribed by Andreas Flörsheimer; Maria-Regina Kula


Publisher
Springer Vienna
Year
1988
Tongue
English
Weight
391 KB
Volume
119
Category
Article
ISSN
0026-9247

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Papain catalyzed synthesis of glyceryl e
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Papain catalyzed synthesis of glyceryl esters of BOC(Z)-protected amino acids and peptides was performed at 40-50°C in a 50 molar excess of glycerol. Equilibrium was achieved in 6-7 h. The maximal yield of esters (50-70%) was obtained at 10% of water and pH 3.2-3.4. A lower water concentration resul