Purification of Microsomal and Mitochondrial 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase from Human Placenta
✍ Scribed by Van Luu-The; Masakazu Takahashi; Fernand Labrie
- Book ID
- 119864886
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 277 KB
- Volume
- 595
- Category
- Article
- ISSN
- 0890-6564
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The activity of 3 beta-hydroxysteroid dehydrogenase delta 4-5 isomerase (3 beta-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of 13 subjects. The sebaceous gland possessed the highest activity of 3 beta-HSD in the skin, while the apocrine sweat gland showed only
The 3__β__‐hydroxysteroid dehydrogenase/__Δ__5‐__Δ__4‐isomerase (3__β__‐HSD) enzymes are essential for the biosynthesis of steroid hormones. The 3__β__‐HSD gene family has been reported to encode for different isoenzymes which function either as dehydrogenase/isomerase or as reductase. The 3__β__‐HS