Solubilization of Δ5-3β-hydroxysteroid dehydrogenase with Δ5−Δ4 isomerase and 17β-hydroxysteroid dehydrogenase from rat testicular microsomal fraction by several detergents
✍ Scribed by Hiroshi Inano; Junko Hayashiyama; Bun-Ichi Tamaoki
- Book ID
- 116002563
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 614 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-4731
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The 3__β__‐hydroxysteroid dehydrogenase/__Δ__5‐__Δ__4‐isomerase (3__β__‐HSD) enzymes are essential for the biosynthesis of steroid hormones. The 3__β__‐HSD gene family has been reported to encode for different isoenzymes which function either as dehydrogenase/isomerase or as reductase. The 3__β__‐HS
## Abstract Little information is available for neurosteroidogenesis in the central nervous system (CNS) of lower vertebrates. Therefore, in the present study, we examined the enzymatic activity and localization of 3β‐hydroxysteroid dehydrogenase/Δ^5^‐Δ^4^‐isomerase (3βHSD), a key steroidogenic enz