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Purification of adenoviral vectors using expanded bed chromatography

✍ Scribed by C. Peixoto; T.B. Ferreira; M.J.T. Carrondo; P.E. Cruz; P.M. Alves

Book ID
113767163
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
208 KB
Volume
132
Category
Article
ISSN
0166-0934

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## Abstract ## Background Adenoviral vectors are used extensively in human gene therapy trials and in vaccine development. Large‐scale GMP production requires a downstream purification process, and liquid chromatography is emerging as the most powerful mode of purification, enabling the production