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Improved purification of recombinant adenoviral vector by metal affinity membrane chromatography

✍ Scribed by Dong-Sop Lee; Byong-Moon Kim; Dai-Wu Seol

Book ID
116297813
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
191 KB
Volume
378
Category
Article
ISSN
0006-291X

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## Abstract ## Background Adenoviral vectors are used extensively in human gene therapy trials and in vaccine development. Large‐scale GMP production requires a downstream purification process, and liquid chromatography is emerging as the most powerful mode of purification, enabling the production