## Abstract Stable E1 transformed cells, like PER.C6, are able to grow at scale and to high cell densities. E1‐deleted adenoviruses replicate to high titer in PER.C6 cells whereas subsequent deletion of E2A from the vector results in absence of replication in PER.C6 cells and drastically lowers the
✦ LIBER ✦
Towards purification of adenoviral vectors based on membrane technology
✍ Scribed by Cristina Peixoto; Tiago B. Ferreira; Marcos F. Q. Sousa; Manuel J. T. Carrondo; Paula M. Alves
- Publisher
- American Institute of Chemical Engineers
- Year
- 2008
- Tongue
- English
- Weight
- 166 KB
- Volume
- 24
- Category
- Article
- ISSN
- 8756-7938
- DOI
- 10.1002/btpr.25
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