## Abstract Microsatellite instability (MSI) and mutations in the PTEN gene are among the molecular alterations involved in endometrial carcinogenesis. There is conflicting information regarding to their role in this type of tumor. For this reason, we have studied both molecular lesions in a large
β¦ LIBER β¦
PTEN gene mutations in colorectal cancers displaying microsatellite instability
β Scribed by Ki-Hyuk Shin; Young Jin Park; Jae-Gahb Park
- Book ID
- 117467094
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 126 KB
- Volume
- 174
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The relationship between microsatellite
β
Cristina Bilbao; GermΓ‘n RodrΓguez; Raquel RamΓrez; Orlando FalcΓ³n; Laureano LeΓ³n
π
Article
π
2006
π
John Wiley and Sons
π
French
β 216 KB
PTEN mutations are common in sporadic mi
β
Nassif, Najah T; Lobo, Glenn P; Wu, Xiaojuan; Henderson, Christopher JA; Morriso
π
Article
π
2004
π
Nature Publishing Group
π
English
β 484 KB
Somatic mutation of the PTEN/MMAC1 gene
β
Kaori Minobe; Koichi Bando; Koichi Fukino; Sachi Soma; Fujio Kasumi; Goi Sakamot
π
Article
π
1999
π
Elsevier Science
π
English
β 199 KB
Microsatellite Instability and Mutations
Microsatellite Instability and Mutations in DNA Mismatch Repair Genes in Sporadic Colorectal Cancers
β
Seung-Yong Jeong
π
Article
π
2003
π
Springer
π
English
β 488 KB
Frameshift Mutations at Mononucleotide R
β
Ikenoue, Tsuneo ;Togo, Goichi ;Nagai, Keiichi ;Ijichi, Hideaki ;Kato, Jun ;Yamaj
π
Article
π
2001
π
Wiley (Blackwell Publishing)
π
English
β 107 KB
Novel mutations of the suppressor gene P
β
Stine A. Danielsen; Guro E. Lind; Merete BjΓΈrnslett; Gunn I. Meling; Torleiv O.
π
Article
π
2009
π
John Wiley and Sons
π
English
β 69 KB
In conclusion, PTEN contributes in maintaining normal cell homeostasis, and the numerous alterations found in several sporadic tumor types emphasize the significance of this tumor suppressor gene. Somatic PTEN mutations appear to play an important role in the development of a subgroup of sporadic co