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Psychopharmacological profile of a new chroman derivative with 5-hydroxytryptamine1A agonist properties: S 20499 (+)

✍ Scribed by Roger D. Porsolt; Antoine Lenègre; Daniel H. Caignard; Bruno Pfeiffer; Elisabeth Mocaër; Beatrice Guardiola-Lemaître


Book ID
102816497
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
795 KB
Volume
27
Category
Article
ISSN
0272-4391

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Anxiolytic properties of (+) s 20499, a
✍ Peter F. Curle; Elisabeth Mocaer; Pierre Renard; Béatrice Guardiola 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 854 KB

Previous studies have shown that (\*) S 20244 (8-(4-[N-(5-methoxychroman-3-yl) N-propylamino] butyl) 8-azaspiro[4,5]decane-7,9 dione) and its isomers ( + ) S 20499 and (-) S 20500 are full agonists at 5-HT,, receptors. In the present study, the effects of these three compounds were investigated in t