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Effects of two 5-HT1A agonist with anxiolytic properties: S 14506 and S 20499, on sleep-wakefulness regulations in the rat

✍ Scribed by Adrien, J.; Desfemmes, T.; Maudhuit, C.; Hamon, M.

Book ID
122754022
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
76 KB
Volume
3
Category
Article
ISSN
0924-977X

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Previous studies have shown that (\*) S 20244 (8-(4-[N-(5-methoxychroman-3-yl) N-propylamino] butyl) 8-azaspiro[4,5]decane-7,9 dione) and its isomers ( + ) S 20499 and (-) S 20500 are full agonists at 5-HT,, receptors. In the present study, the effects of these three compounds were investigated in t