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Psoriasis Is Not Associated with IL-12p70/IL-12p40 Production and IL12B Promoter Polymorphism

✍ Scribed by Litjens, Nicolle H.R.; van der Plas, Mariena J.A.; Ravensbergen, Bep; Numan-Ruberg, Sandra C.; van Assen, Yvette; Thio, H. Bing; van Dissel, Jaap T.; van de Vosse, Esther; Nibbering, Peter H.

Book ID: 110733140
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 139 KB
Volume: 122
Category: Article
ISSN: 0022-202X
DOI: 10.1111/j.0022-202x.2004.22427.x

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## Abstract The interleukin-12p40 gene (IL12B) encodes the p40 polypeptide chain, which, together with p19, composes IL-23. A bi-allelic promoter polymorphism (IL12Bpro) located at −2703 bp of the transcription initiation site has been reported to show associations with IL-12p40 production. To eluc