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Pseudopeptide synthesis of a pentaazamacrocycle containing two trans-fused cyclohexane rings

✍ Scribed by William L Neumann; Gary W. Franklin; Kirby R. Sample; Karl W. Aston; Randy H. Weiss; Dennis P. Riley; Nigam Rath

Book ID
104256927
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
163 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

The synthesis of a bis-cyclohexyl-fused penlaazamacrocycle via head-to-tail pseudopeptide cyclization chemistry is described. The bis-cyclohexyl-fused cyclic pseudopeptide 11 displays intramolecular hydrogen bonding which has been characterized by variable temperature NMR spectroscopy and X-Ray Crystallography.

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