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Pseudoceratinazole A: a novel bromotyrosine alkaloid from the Australian sponge Pseudoceratina sp.

✍ Scribed by Yunjiang Feng; Rohan A. Davis; Melissa L. Sykes; Vicky M. Avery; David Camp; Ronald J. Quinn

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 371 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.07.052

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✦ Synopsis

Mass-directed fractionation based on a Trypanosoma brucei brucei active fraction from the Australian sponge Pseudoceratina sp. led to the isolation of a novel bromotyrosine alkaloid, pseudoceratinazole A (1). Compound 1 is the first dimeric bromotyrosine alkaloid containing an imidazole-bridging moiety.

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