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Prox1, master regulator of the lymphatic vasculature phenotype

โœ Scribed by Young-Kwon Hong; Michael Detmar

Book ID
106138605
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
256 KB
Volume
314
Category
Article
ISSN
0302-766X

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An essential role for Prox1 in the induc
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
โœ Wigle, J. T. ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 477 KB

The process of angiogenesis has been well documented, but little is known about the biology of lymphatic endothelial cells and the molecular mechanisms controlling lymphangiogenesis. The homeobox gene Prox1 is expressed in a subpopulation of endothelial cells that, after budding from veins, gives ri