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Prox1 Function Is Required for the Development of the Murine Lymphatic System

✍ Scribed by Jeffrey T Wigle; Guillermo Oliver

Book ID
117268280
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
546 KB
Volume
98
Category
Article
ISSN
0092-8674

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An essential role for Prox1 in the induc
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
✍ Wigle, J. T. πŸ“‚ Article πŸ“… 2002 πŸ› Nature Publishing Group 🌐 English βš– 477 KB

The process of angiogenesis has been well documented, but little is known about the biology of lymphatic endothelial cells and the molecular mechanisms controlling lymphangiogenesis. The homeobox gene Prox1 is expressed in a subpopulation of endothelial cells that, after budding from veins, gives ri