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Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

✍ Scribed by Petrova, T. V.

Book ID
111749681
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
249 KB
Volume
21
Category
Article
ISSN
0261-4189

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## Abstract Transcription factor Ets‐1 is induced in endothelial cells (ECs) by angiogenic factors, and promotes angiogenesis by inducing angiogenesis‐related genes such as MMPs and integrin Ξ²3. Here, we examined the effect of Ets‐1 on apoptosis in ECs. Overexpression of Ets‐1 in human umbilical ve