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Provisional assignment of the gene for uridine monophosphatase-2 (Umph-2) to mouse chromosome 11

✍ Scribed by Dwight E. Wilson; David Woodard; Abby Sandler; Jill Erickson; Austin Gurney

Publisher
Springer
Year
1987
Tongue
English
Weight
250 KB
Volume
25
Category
Article
ISSN
0006-2928

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✦ Synopsis

The segregation of the mouse gene for uridine monophosphatase-2 (Umph-2) was examined in 14 independent mouse-Syrian hamster hybrids and 10 hybrid subclones. Umph-2 cosegregated with the mouse galactokinase (Glk) gene in 23 of the 24 hybrids and showed at least four discordances with all other mouse marker isozymes examined. The observed synteny of Umph-2 and Glk, which has also been observed in humans, indicates that the mouse Umph-2 gene is on chromosome 11.

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