Proton magnetic resonance studies of compounds with bridgehead nitrogen. Part 39. Stereochemistry of perhydropyrido[3,2,1-ij][3,1]benzoxazines and the conformational equilibrium for perhydropyrido[1,2-c][1,3]oxazine
✍ Scribed by Crabb, Trevor A.; Turner, Christopher H.
- Book ID
- 120195017
- Publisher
- Royal Society of Chemistry
- Year
- 1980
- Tongue
- English
- Weight
- 581 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1472-779X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Protonation of perhydrooxazolo[3,4-a~pyridine, perhydropyrido[1,2-~~[1,3]oxazine and perhydropyridoI 1,2c][ 1,310xazepine by hydrogen chloride gas in diethyl ether gave mixtures of trans-and cis-fused hydrochlorides containing 28, 75 and 79% of the trans-fused salts, respectively, which compare with
## Abstract Low‐temperature ^13^C NMR spectroscopy shows perhydropyrido [1,2‐__c__] [1,3]oxazine to adopt a conformational equilibrium in CD~2~Cl~2~–CFCl~3~ solution containing 98% __trans__ fused conformer in equilibrium with 2% __O__‐outside‐__cis__ fused conformer at 203 K. A similar equilibrium
## Abstract The 270 MHz NMR data on __trans__‐ and __cis__‐(H‐4a, H‐7)‐7‐ethylperhydropyrido[1,2‐__c__][1,3]thiazine show heavy conformational bias to the __trans__‐ and __S__‐inside __cis__‐fused conformations, respectively. Comparison of the ^13^C NMR spectra of these anancomeric systems with the
## Abstract A series of perhydropyrido[1,2‐__c__][1,6,3]dioxazocines and 2‐alkylperhydropyrido[1,2‐__c__][1,3,6]oxdiazocines have been prepared. 6‐__p__‐Nitrophenyl‐3,4‐dimethylperhydropyrido[1,2‐__c__][1,6,3]‐dioxazodioxazocine is shown to adopt the __cis__ fused ring conformation in solution with
## Abstract The configurations and conformations of diastereoisomeric 1‐(decahydroquinolin‐8‐yl)butan‐2‐ols and of perhydropyrido[3,2,1‐__j,k__][3,1]benzoxazepines resulting from ring closure of these compounds with formaldehyde have been assigned by ^1^H and ^13^C NMR spectroscopy.