Solvation of the active site of cytochro
โ
Rebecca C. Wade
๐
Article
๐
1990
๐
Springer Netherlands
๐
English
โ 372 KB
Energetically favorable water binding sites in the substrate pocket ofcytochrome P450-cam have been predicted by a molecular mechanics method. Binding sites corresponding to all the experimentally observed water sites in this region of the enzyme were located. The calculations also indicate the pres