𝔖 Bobbio Scriptorium
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Models for the enzymatically active state of cytochrome p-450

✍ Scribed by Gilda H. Loew; Leonard M. Hjelmeland; Robert F. Kirchner


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
997 KB
Volume
12
Category
Article
ISSN
0020-7608

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Energetically favorable water binding sites in the substrate pocket ofcytochrome P450-cam have been predicted by a molecular mechanics method. Binding sites corresponding to all the experimentally observed water sites in this region of the enzyme were located. The calculations also indicate the pres