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Conformational States of Cytochrome P450cam Revealed by Trapping of Synthetic Molecular Wires

✍ Scribed by Anna-Maria A. Hays; Alexander R. Dunn; Richard Chiu; Harry B. Gray; C. David Stout; David B. Goodin


Book ID
116661684
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
990 KB
Volume
344
Category
Article
ISSN
0022-2836

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Two-state reactivity mechanisms of hydro
✍ Sason Shaik; SamuΓ«l P de Visser; FranΓ§ois Ogliaro; Helmut Schwarz; Detlef SchrΓΆd πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 199 KB

Recent computational studies of alkane hydroxylation and alkene epoxidation by a model active species of the enzyme cytochrome P-450 reveal a two-state reactivity (TSR) scenario in which the information content of the product distribution is determined jointly by two states. TSR is used to reconcile