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Proteolytic degradation of fused protein A-β-galactosidase in Escherichia coli

✍ Scribed by Hellebust, Halldis; Veide, Andres; Enfors, Sven-Olof


Book ID
121961228
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
745 KB
Volume
7
Category
Article
ISSN
0168-1656

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Ten out of 43 missense mutations in the lacZ gene of Escherchia coli gave rise to polypeptide chains that were degraded in vivo. While many of the mutants appeared to be fully or partially CRM-, there appeared to be no obvious correlation between degradation, map position, altered subunit associatio