The description in the past year of several novel protein tyrosine kinase inhibitors, which exhibit dramatic improvements in potency and specificity over earlier agents, will be considered a major turning point in the field. These compounds appear to have the necessary pharmacological properties to
โฆ LIBER โฆ
Protein Tyrosine Kinases. From Inhibitors to Useful Drugs
โ Scribed by Hochhaus, A
- Book ID
- 110056794
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 38 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0887-6924
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## Abstract Protein kinases play a crucial role in signal transduction as well as in cellular proliferation, differentiation, and various regulatory mechanisms. The inhibition of growth related kinases, especially tyrosine kinases, might provide new therapies for diseases such as cancer. The progre