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Inhibitors of Protein Tyrosine Phosphatases: Next-Generation Drugs?

✍ Scribed by Laurent Bialy; Herbert Waldmann


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Protein–tyrosine phosphatases: Structure
✍ Terrence R. Burke Jr.; Zhong-Yin Zhang πŸ“‚ Article πŸ“… 1998 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 224 KB πŸ‘ 2 views

Protein-tyrosine kinases (PTKs) and their associated signaling pathways are crucial for the regulation of numerous cell functions including growth, mitogenesis, motility, cell-cell interactions, metabolism, gene transcription, and the immune response. Since tyrosine phosphorylation is reversible and