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Protein synthesis is required for optimal induction of 25-hydroxyvitamin D3-24-hydroxylase, osteocalcin, and osteopontin mRNA by 1,25-dihydroxyvitamin D3

โœ Scribed by Claudia Zierold; Jamie A Mings; Jean M Prahl; Greg G Reinholz; Hector F DeLuca


Book ID
117042110
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
271 KB
Volume
404
Category
Article
ISSN
0003-9861

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Regulation of 25-hydroxyvitamin D3-24-hy
โœ Claudia Zierold; Jamie A. Mings; Hector F. DeLuca ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 100 KB

## Abstract The 25โ€hydroxyvitamin D~3~โ€24โ€hydroxylase mRNA is tightly and reciprocally regulated by 1,25โ€dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24โ€hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu