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Distribution of 1,25-Dihydroxyvitamin-D3 Receptor and 25-Hydroxyvitamin-D3-24-Hydroxylase mRNA Expression along Rat Nephron Segments

✍ Scribed by K. Iida; S. Taniguchi; K. Kurokawa

Book ID
115573254
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
380 KB
Volume
194
Category
Article
ISSN
0006-291X

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu