Linear response theory in dihedral angle
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Satoshi Omori; Sotaro Fuchigami; Mitsunori Ikeguchi; Akinori Kidera
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Article
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2009
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John Wiley and Sons
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English
โ 429 KB
## Abstract Coupling between proteins motion and ligand binding can be well explained by the linear response theory (Ikeguchi, M.; Ueno, J.; Sato, M.; Kidera, A. Phys Rev Lett 2005, 94, 078102.), in which the structural change is treated as a response to ligand binding. The prediction accuracy of s