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Molecular structure of malate synthase and structural changes upon ligand binding to the enzyme

โœ Scribed by G. Schmid; H. Durchschlag; G. Biedermann; H. Eggerer; R. Jaenicke


Book ID
118309321
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
447 KB
Volume
58
Category
Article
ISSN
0006-291X

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Growth factor receptor-bound protein 2 (Grb2) is an extensively studied adaptor protein involved in cell signaling. Grb2 is a highly flexible protein composed of a single SH2 domain flanked by two SH3 domains. Here we report on the structural dynamic effects upon interaction of a phosphopeptide liga