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Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor‐β pathway

✍ Scribed by David L. Bruce; Thomas Macartney; Weidong Yong; Weinian Shou; Gopal P. Sapkota


Book ID
118428425
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
858 KB
Volume
24
Category
Article
ISSN
0898-6568

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## Abstract Transforming growth factor‐β (TGF‐β), a multifunctional cytokine, has been widely suggested to play a role in the pathogenesis of Alzheimer's disease. Supporting this, levels of TGF‐β are elevated in the cerebrospinal fluid, sera, and brain of patients with Alzheimer's disease. Since TG