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Protein Kinase D1 Mediates Mitogenic Signaling in Human Pancreatic Carcinoma PANC-1 Cells

✍ Scribed by Sinnett-Smith, James ;Guha, Sushovan ;Kisfalvi, Krisztina ;Rozengurt, Enrique

Book ID
122187871
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
52 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Neurotensin (NT) stimulates protein kinase D1 (PKD1), extracellular signal regulated kinase (ERK), c‐Jun N‐terminal Kinase (JNK), and DNA synthesis in the human pancreatic adenocarcinoma cell line PANC‐1. To determine the effect of PKD1 overexpression on these biological responses, we g