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Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2

✍ Scribed by Fanfan Zhou; Andy C Lee; Katja Krafczyk; Ling Zhu; Michael Murray


Book ID
111219769
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
941 KB
Volume
162
Category
Article
ISSN
0007-1188

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The organic anion transporting polypeptide (OATP) of the basolateral hepatocyte membrane mediates multispecific uptake of anionic and other amphipathic substrates from sinusoidal blood plasma. To investigate the mechanisms controlling OATP expression, the 5'-flanking region of the human OATP gene wa