The organic anion transporting polypeptide (OATP) of the basolateral hepatocyte membrane mediates multispecific uptake of anionic and other amphipathic substrates from sinusoidal blood plasma. To investigate the mechanisms controlling OATP expression, the 5'-flanking region of the human OATP gene wa
Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene
β Scribed by G Kullak-Ublick; U Beuers; C Fahney; B Hagenbuch; PJ Meier; G Paumgartner
- Book ID
- 118686709
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 300 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0270-9139
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π SIMILAR VOLUMES
To characterize the transport functions of a recently cloned basolateral organic anion transporting polypeptide of rat hepatocytes we performed further kinetic transport and substrate cis-inhibition studies in organic anion-transporting polypeptide-cRNA injected Xenopus Zaevis oocytes. The studies d
## Abstract Postreplicative mismatch repair (MMR) corrects polymerase errors arising during DNA replication. Consistent with this role, the __Saccharomyces cerevisiae MMR__ genes __MSH2, MSH6,__ and __PMS1__ were reported to be transcriptionally upregulated during late G~1~ phase of the cell cycle.