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Protein Kinase C Is a Mediator of the Synthesis and Secretion of Osteoprotegerin in Osteoblast-like Cells

โœ Scribed by Xuhao Yang; David Halladay; Jude E. Onyia; T.John Martin; Srinivasan Chandrasekhar

Book ID
115589217
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
95 KB
Volume
290
Category
Article
ISSN
0006-291X

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Protein kinase C activation inhibits str
Protein kinase C activation inhibits stress-induced synthesis of heat shock protein 27 in osteoblast-like cells: Function of arachidonic acid
โœ Atsushi Suzuki; Osamu Kozawa; Yutaka Oiso; Kanefusa Kato ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 616 KB

Exposure of osteoblast-like MC3T3-El cells to sodium arsenite (arsenite) increased the level of heat shock protein 27 (hsp27). The effect of arsenite was dose-dependent in the range of 50 to 200 pM. Arsenite also stimulated arachidonic acid release dose-dependently in the range between 50 and 200 pM