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Protein complexes and proteome organization from yeast to man

✍ Scribed by Anne-Claude Gavin; Giulio Superti-Furga

Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
343 KB
Volume
7
Category
Article
ISSN
1367-5931

No coin nor oath required. For personal study only.

✦ Synopsis

Protein complexes may well be the most relevant molecular units of cellular function. The activities of protein complexes have to be regulated both in time and space to integrate within the overall cell programs. The cell can be compared to a factory orchestrating individual assembly lines into integrated networks fulfilling particular and superimposed tasks. Recent proteome-wide studies provide insight into the properties of cellular protein complexes, their modular nature, their interaction with other complexes and the resulting preliminary organization chart of the proteome.

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