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From the analysis of protein complexes to proteome-wide linkage maps

✍ Scribed by Pierre Legrain; Jean-Luc Jestin; Vincent Schächter

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
86 KB
Volume
11
Category
Article
ISSN
0958-1669

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✦ Synopsis

Recent advances in genomics have led to the accumulation of an unprecedented amount of data about genes. Proteins, not genes, however, sustain function. The traditional approach to protein function analysis has been the design of smart genetic assays and powerful purification protocols to address very specific questions concerning cellular mechanisms. Lately, a number of proteome-wide functional strategies have emerged, giving rise to a new field in biology, proteomics, that addresses the biology of a cell as a whole.

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