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Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model

✍ Scribed by Therese Östberg; Kohki Kawane; Shigekazu Nagata; Huan Yang; Sangeeta Chavan; Lena Klevenvall; Marco E. Bianchi; Helena Erlandsson Harris; Ulf Andersson; Karin Palmblad


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
409 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the role of the novel cytokine high mobility group box chromosomal protein 1 (HMGB‐1) in the pathogenesis of cutaneous lupus erythematosus (CLE). ## Methods Punch biopsy specimens of lesional and unaffected skin from 10 patients with CLE and 3 healthy cont