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High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis

✍ Scribed by Luis Ulloa; Franak M. Batliwalla; Ulf Andersson; Peter K. Gregersen; Kevin J. Tracey


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
64 KB
Volume
48
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the role of the novel cytokine high mobility group box chromosomal protein 1 (HMGB‐1) in the pathogenesis of cutaneous lupus erythematosus (CLE). ## Methods Punch biopsy specimens of lesional and unaffected skin from 10 patients with CLE and 3 healthy cont