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High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis

✍ Scribed by Rille Pullerits; Ing-Marie Jonsson; Margareta Verdrengh; Maria Bokarewa; Ulf Andersson; Helena Erlandsson-Harris; Andrej Tarkowski


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
284 KB
Volume
48
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the role of the novel cytokine high mobility group box chromosomal protein 1 (HMGB‐1) in the pathogenesis of cutaneous lupus erythematosus (CLE). ## Methods Punch biopsy specimens of lesional and unaffected skin from 10 patients with CLE and 3 healthy cont