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Protective role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in cisplatin-induced nephrotoxicity

โœ Scribed by Gang, Gil-Tae; Kim, Yong-Hoon; Noh, Jung-Ran; Kim, Kyoung-Shim; Jung, Ju-Young; Shong, Minho; Hwang, Jung Hwan; Lee, Chul-Ho

Book ID
120513750
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
767 KB
Volume
221
Category
Article
ISSN
0378-4274

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Targeting NAD(P)H:quinone oxidoreductase
Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer
โœ Anne M. Lewis; Matthew Ough; Marilyn M. Hinkhouse; Ming-Sound Tsao; Larry W. Obe ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 435 KB

## Abstract NAD(P)H:quinone oxidoreductase (NQO1) functions as an important part of cellular antioxidant defense by detoxifying quinones, thus preventing the formation of reactive oxygen species (ROS). The aim of our study was to determine if NQO1 is elevated in pancreatic cancer specimens and panc