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NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones

โœ Scribed by David Siegel; Chao Yan; David Ross

Book ID
113489708
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
575 KB
Volume
83
Category
Article
ISSN
0006-2952

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โœ Anne M. Lewis; Matthew Ough; Marilyn M. Hinkhouse; Ming-Sound Tsao; Larry W. Obe ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 435 KB

## Abstract NAD(P)H:quinone oxidoreductase (NQO1) functions as an important part of cellular antioxidant defense by detoxifying quinones, thus preventing the formation of reactive oxygen species (ROS). The aim of our study was to determine if NQO1 is elevated in pancreatic cancer specimens and panc