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Hypermethylation of NAD(P)H: quinone oxidoreductase 1 (NQO1) gene in human hepatocellular carcinoma

โœ Scribed by Motohisa Tada; Osamu Yokosuka; Kenichi Fukai; Tetsuhiro Chiba; Fumio Imazeki; Takeshi Tokuhisa; Hiromitsu Saisho


Book ID
116650572
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
290 KB
Volume
42
Category
Article
ISSN
0168-8278

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Targeting NAD(P)H:quinone oxidoreductase
โœ Anne M. Lewis; Matthew Ough; Marilyn M. Hinkhouse; Ming-Sound Tsao; Larry W. Obe ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 435 KB

## Abstract NAD(P)H:quinone oxidoreductase (NQO1) functions as an important part of cellular antioxidant defense by detoxifying quinones, thus preventing the formation of reactive oxygen species (ROS). The aim of our study was to determine if NQO1 is elevated in pancreatic cancer specimens and panc