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Protective role of heme oxygenase-1 induction in carbon tetrachloride-induced hepatotoxicity

โœ Scribed by Kiichi Nakahira; Toru Takahashi; Hiroko Shimizu; Kyoichiro Maeshima; Kenji Uehara; Hiromi Fujii; Hideki Nakatsuka; Masataka Yokoyama; Reiko Akagi; Kiyoshi Morita

Book ID
113993649
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
821 KB
Volume
66
Category
Article
ISSN
0006-2952

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Heme oxygenase-1 (HO-1) is a stress protein induced in response to a variety of oxidative challenges. After treatment of the hybrid septal cells SN 56 with โค-amyloid peptide (โค-AP 1-40 ) or hydrogen peroxide (H 2 O 2 ), we detected high levels of reactive oxygen species, accompanied by a significant