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Protective effects of Vitamin C on cisplatin nephrotoxicity

✍ Scribed by Se-Young Choung; Jae-Myeong Kong

Book ID
112961554
Publisher
Springer
Year
1994
Tongue
English
Weight
825 KB
Volume
17
Category
Article
ISSN
0253-6269

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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r