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Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition

✍ Scribed by Sarah K. Kidd; Jay S. Schneider

Book ID
113505136
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
666 KB
Volume
1354
Category
Article
ISSN
0006-8993

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## Abstract The critical observation in the pathology of Parkinson's disease (PD) is that neurodegeneration is largely restricted to dopaminergic neurons that develop cytoplasmic inclusions called Lewy bodies. These aggregations contain the protein α‐synuclein. Furthermore, it is becoming apparent