Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies
β Scribed by Heinz Ludwig; David Khayat; Giuseppe Giaccone; Thierry Facon
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 177 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __cβSrc__ was the first protooncogene described and was among the first molecules in which tyrosine kinase activity was documented. cβSrc has been defined as a common modular structure that participates in much of the crosstalk between the cytoplasmic protein tyrosine kinases and tyrosi
## Abstract Clofarabine is a newβgeneration nucleoside analog that has been synthesized to combine the most favorable pharmacokinetic properties of its congeners fludarabine and cladribine. In addition to inhibition of DNA polymerases and DNA synthesis, clofarabine acts as a strong inhibitor of rib
## Abstract Tumor necrosis factor (TNF), originally identified as a factor produced in the serum of endotoxinβinjected animals, is a cytokine that mediates tumor necrosis. To date, 20 different members of the TNF superfamily and 21 different receptors have been identified. All ligands of the TNF su